Activins and Inhibins by Gerald Litwack

By Gerald Litwack

First released in 1943, Vitamins and Hormones is the longest-running serial released via educational Press. The Editorial Board now displays services within the box of hormone motion, diet motion, X-ray crystal constitution, body structure, and enzyme mechanisms.

Under the able and certified editorial management of Dr. Gerald Litwack, Vitamins and Hormones maintains to submit state-of-the-art reports of curiosity to endocrinologists, biochemists, nutritionists, pharmacologists, telephone biologists, and molecular biologists. Others attracted to the constitution and serve as of biologically energetic molecules like hormones and supplements will, as continuously, flip to this sequence for complete stories via best individuals to this and comparable disciplines.

This quantity specializes in activins and inhibins.

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And Vassalli, J. D. (1994). TGF-beta 1 influences the relative development of the exocrine and endocrine pancreas in vitro. Development 120, 3451–3462. Schier, A. , and Shen, M. M. (2000). Nodal signalling in vertebrate development. Nature 403, 385–389. , and Hill, C. S. (2007). TGFbeta-SMAD signal transduction: Molecular specificity and functional flexibility. Nat. Rev. Mol. Cell Biol. 8, 970–982. , Jenkins, N. , Gilbert, D. , Copeland, N. , and Schrewe, H. (1996). Structure, chromosomal localization, and expression analysis of the mouse inhibin/activin beta C (Inhbc) gene.

Activin/Nodal Signaling and Pluripotency 43 2. Derivation of ESCs Although ESCs research, particularly human ESCs research, is perceived as a phenomenon that emerged in the past decade, the developments in this field are deeply rooted in research and accomplishments that date back to the 1950s. In 1954, Stevens and Little first described an incidence of spontaneous testicular teratomas, which were histologically similar to typical teratomas but were malignant, in the inbred 129/terSv mouse strain (Stevens and Little, 1954).

Acta 1446, 233–242. , and Ogata, E. (1988). A novel action of activin A: Stimulation of insulin secretion in rat pancreatic islets. Biochem. Biophys. Res. Commun. 156, 335–339. , Sawchenko, P. , and Vale, W. W. (1996). Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain. Mol. Cell. Neurosci. 7, 467–478. , and Sugino, H. (2004). Activin isoforms signal through type I receptor serine/threonine kinase ALK7. Mol. Cell. Endocrinol. 220, 59–65.

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