Advances in Cancer Research, Vol. 15 by George Klein, Sidney Weinhouse, Alexander Haddow (Eds.)

By George Klein, Sidney Weinhouse, Alexander Haddow (Eds.)

Show description

Read or Download Advances in Cancer Research, Vol. 15 PDF

Best oncology books

You Don't Have to Suffer: A Complete Guide to Relieving Cancer Pain for Patients and Their Families

On March 2, 1994, the business enterprise for future health Care coverage and learn (a department of the general public healthiness carrier) made headlines via liberating new melanoma ache administration guidance. That document printed that ache is often undertreated, and that aid isn't just attainable for many sufferers, yet really aids in restoration.

Drug Delivery in Oncology: From Basic Research to Cancer Therapy

During this first authoritative assessment on glossy melanoma chemotherapy 121 foreign experts have contributed their adventure and up to date facts for what's prone to develop into the premier within the box. The authors summarize wisdom received over the last decade, from simple suggestions to winning functions within the health facility, masking lively and passive focusing on concepts in addition to tissue-specific techniques.

Chemotherapy-induced neuropathic pain

''Written for soreness administration Practitioners, Oncologists, Oncology Nurses, Nurse Practitioners, Social staff, Pharmacologists, and first Care Practitioners, in addition to scholars in those fields, this reference presents perception into chemotherapy-induced neuropathic soreness melanoma survivors endure. It experiences the fundamental and scientific learn into the traditional body structure of soreness transmission pathways, neuropathic soreness pathology, the chemotherapeutic drug mechanisms of motion and hostile results, chemotherapy-induced neuropathy, and drug discovery efforts for remedy.

Ovarian Cancer with Expert Consult

Every one quantity within the Early Detection and remedy of melanoma sequence is jam-packed with functional, authoritative details designed to hide the entire diversity of diagnostic methods, together with pathologic, radiologic, bronchoscopic, and surgical facets. You’ll be ready to ascertain the most secure, shortest, least invasive technique to succeed in a correct prognosis; degree the sickness; and select the simplest preliminary remedy for early levels.

Additional resources for Advances in Cancer Research, Vol. 15

Example text

A tumor virus may bring about changes in transformed cells other than the development of TSTA, and some of these changes may represent new antigenicities. Therefore, it cannot be said that different in vitro tests all measure TSTA. For this reason, the antigen or antigens detected by in vitro tests will be designated as surface or S-antigen(s) . I n this section, we will analyze the S-antigen(s) with respect to their detection, specificity, and nature. Tevethia et al. (1965) first demonstrated S-antigen in SV40-transformed cells by the indirect immunofluorescence test using sera from SV40-vaccinated hamsters that had rejected a transplant of virus-free SV40 tumor cells.

The oncogenicity of SV40 can also be prevented by inoculating hamsters in the latent period before tumor appearance with nontransplantable syngeneic or xenogeneic SV40-transformed cells. Using this method, Girardi (1965) demonstrated the cross-reactivity between the TSTA of SV40-transformed human cells and that of SV40-transformcd hamster cells. F. Jensen and Defendi (1968) used the same technique to demonstrate the absence of SV40 TSTA in simian cells transformed by ultraviolet light-irradiated defective SV40 (PARA), However, it should be pointed out that these latter cells were not tested for their ability to immunize hamsters against challenge with an immunosensitive SV40 tumor cell line.

A. , 1963; Koch and Sabin, 1963). , 1964a; Pope and Rowe, 20 J. S. BUTEL, S. S. TEVETHIA, AXD J . L. MELNICK 1964). A typical pattern of nuclear fluorescence by SV40 T-antigen is shown in Fig. 1. , 1965). Kinctic studies showed that T-antigen appears 12-24 hours after infection with SV40, prior to the appearance of viral capsid antigen and progeny virions. , 1965a). 1. Inimunofluorescence detection of SV40 T-antigen localized in nucleus of rell. X 400. PAPOVAVIRUS SV40 21 originating from different species are antigenically similar.

Download PDF sample

Rated 4.77 of 5 – based on 18 votes