Anthracycline Antibiotics. New Analogues, Methods of by Waldemar Priebe

By Waldemar Priebe

content material: Unresolved structure-activity relationships in anthracycline analogue improvement / Edward M. Acton --
Non-cross-resistant anthracyclines with decreased basicity and elevated balance of the glycosidic bond / Waldemar Priebe, Piotr Skibicki, Oscar Varela, Nouri Neamati, Marcos Sznaidman, Krzysztof Dziewiszek, Grzegorz Grynkiewicz, Derek Horton, Yiyu Zou, Yi-He Ling, and Roman Perez-Soler --
Fluorinated anthracyclinones and their glycosylated items / Antonio Guidi, Franca Canfarini, Alessandro Giolitti, Franco Pasqui, Vittorio Pestellini, and Federico Arcamone --
Semisynthetic rhodomycins and anthracycline prodrugs / Cenek Kolar, Klaus Bosslet, Jörg Czech, Manfred Gerken, Peter Hermentin, Dieter Hoffmann, and Hans-Harold Sedlacek --
artificial ideas for reversal of anthracycline resistance and cardiotoxicity / Claude Monneret, Jean-Claude Florent, Jean-Pierre Gesson, Jean-Claude Jacquesy, François Tillequin, and Michel Koch --
Synthesis and organic actions of fluorinated daunorubicin and doxorubicin analogues / Tsutomu Tsuchiya and Yasushi Takagi --
Redox chemistry of anthracyclines and use of oxomorpholinyl radicals / Tad H. Koch and Giorgio Gaudiano --
Synthesis of anthraquinone analogues of associated anthracycline / Ping Ge and Richard A. Russell --
Synthesis and examine of structure-activity relationships of latest periods of anthracyclines / Antonino Suarato, Francesco Angelucci, Alberto Bargiotti, Michele Caruso, Daniela Faiardi, Laura Capolongo, Cristina Geroni, Marina Ripamonti, and Maria Grandi --
Molecular acceptance of DNA by means of daunorubicin / Jonathan B. Chaires --
Adducts of DNA and anthracycline antibiotics : constructions, interactions, and actions / Jasmine Y.-T. Wang, Mark Chao, and Andrew H.-J. Wang --
DNA topoisomerases and their inhibition through anthracyclines / Yves Pommier --
Anthracycline antihelicase motion : new mechanism with implications for guanosine-cytidine intercalation specificity / Nicholas R. Bachur, Robin Johnson, Fang Yu, Robert Hickey, and Linda Malkas --
Membrane biophysical parameters influencing anthracycline motion / Ratna Mehta and Thomas G. Burke --
sign transduction platforms in doxorubicin hydrochloride mechanism of motion / Paul Vichi, James track, Jean Hess, and Thomas R. Tritton --
research of multidrug transporter in dwelling cells : software to uptake and unencumber of anthracycline derivatives through drug-resistant K562 cells / Arlette Garnier-Suillerot, Frédéric Frézard, Marie-Nicole Borrel, Elene Pereira, Jolanta Tarasiuk, and Marina Fiallo --
function of reactive-oxygen metabolism in cardiac toxicity of anthracycline antibiotics / James H. Doroshow --
Amelioration of anthracycline-induced cardiotoxicity by way of natural chemical compounds / Donald T. Witiak and Eugene H. Herman --
Use of drug providers to ameliorate the healing index of anthracycline antibiotics / Roman Perez-Soler, Steven Sugarman, Yiyu Zou, and Waldemar Priebe.

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Sample text

Umezawa, H . Carbohydr. Res. 1987, 169, 69. ; Chisato, N . ; Yoneta, T. J. Antibiot. 1988, 41, 988. ; Hermentin, P. J. Carbohydr. Chem. 1989, 8, 247. Florent, J. ; Monneret, C. J. Antibiot. 1989, 22, 1823. ; ACS Symposium Series; American Chemical Society: Washington, DC, 1994. 46 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. ANTHRACYCLINE ANTIBIOTICS Baer, H . ; Mateo, F. H . Can. J. Chem. 1990, 68, 2055. ; Chang, M . ; Takeuchi, T. Abstr. Pap. XV Internat. Carbohydr.

Am. Chem. Soc. , CARB-11, New York, 1981. ; Varela, O. Abstr. Pap. XIth Internat. Carbohydr. Symp. Vancouver, 1982. Naff, M . ; Narayanan, V. , In Anthracycline Antibiotics; El Khadem, H . ; Academic Press, Inc: New York, 1982, p. 1. ; Wolgemuth, R. L. Eur. Pat. 1984, EP116,222, August 22. ; Priebe, W. S. Patent. 1984, 4,427,664, January 24. ; Priebe, W. S. Patent. 1985, 4,562,177, December 31. ; Priebe, W. S. Patent. 1985, 4,537,882, August 27. ; Priebe, W. Carbohydr. Res. 1985, 136, 391. ; Varela, O.

Van, N. ; Perez-Soler, R. Proc. Am. Chem. Soc. , MEDI-40, San Francisco, 1992. ; Van, N. ; Burke, T. ; Perez-Soler, R. Anti-Cancer Drugs 1993, 4, 37. Ther. 1993, 60, 215. ; Matsushima, T. Biomed. Pharmacother. 1987, 41, 214. El Khadem, H . ; Swartz, D. ; Cermak, R. C. J. Med. Chem. 1977, 20, 957. ; Weckerle, W. Carbohydr. Res. 1977, 57, C36. El Khadem, H . ; Swartz, D. L. Carbohydr. Res. 1978, 65, C1. El Khadem, H . ; Swartz, D. Med. Chem. 1981, 24, 112. ; Winter-Mihaly, E. J. Med. Chem. 1979, 22, 406.

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