Apoptosis Senescence and Cancer by David A Gewirtz (Editor), Shawn Edan Holt (Editor), Steven

By David A Gewirtz (Editor), Shawn Edan Holt (Editor), Steven Grant (Editor)

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Hollstein M, Sidransky D, Vogelstein B, Harris CC. p53 Mutations in Human Cancers. Science 1991; 253(5015):49–53. 261. Di Cristofano A, Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell 2000; 100: 387–90. 262. Hannun YA. Apoptosis and the dilemma of cancer chemotherapy. Blood 1997; 89(6):1845–53. 263. Mow BF, Blajeski AL, Chandra J, Kaufmann SH. Apoptosis and the response to anticancer therapy. Curr Opin Oncol 2001; 13(6):453–62. 264. Belka C, Budach W. Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biology.

233. Lowe SW, Cepro E, Evan G. Intrinsic tumour suppression. Nature 2004:432:307–15. Chapter 1 / The Intrinsic Pathway of Apoptosis 29 234. Gerl R, Vaux DL. Apoptosis in the development and treatment of cancer. Carcinogenesis 2005; 26:263–70. 235. Strasser A, Harris AW, Bath ML, Cory S. Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature 1990; 348(6299):331–3. 236. Pelengaris S, Khan M, Evan GI. Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding. Cell 2001; 107:399–407. 30. Yan N, Shi Y. Mechanisms of apoptosis through structural biology. Ann Rev Cell Dev Biol 2005; 21:35–56. 31. Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Alnemri ES. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol Cell 1998; 1:949–57. 32. Ruchaud S, Korfali N, Villa P, et al. Caspase-6 gene knockout reveals a role for Lamin A cleavage in apoptotic chromatin condensation.

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