Autoimmune Diseases in Endocrinology (Contemporary by Anthony P. Weetman

By Anthony P. Weetman

This can be a complete and novel textual content that examines key good points that predispose members to autoimmune ailments. the 1st part information the elemental mechanism of autoimmunity and examines immunogenetic and environmental elements in autoimmunity. the following part examines autoimmune thyroid affliction. The 3rd part takes a glance at sort 1 diabetes mellitus. within the ultimate part, authors clarify different autoimmune endocrinopathies.

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Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation. J Immunol 2004;173(12):7135–9. 89. Duan L, Reddi AL, Ghosh A, Dimri M, Band H. The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling. Immunity 2004;21(1):7–17. 90. Bachmaier K, Krawczyk C, Kozieradzki I, et al. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature 2000;403(6766):211–6. 91. Yokoi N, Komeda K, Wang HY, et al.

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Walker LS, Abbas AK. The enemy within: keeping self-reactive T cells at bay in the periphery. Nat Rev Immunol 2002;2(1):11–9. 17. Alferink J, Tafuri A, Vestweber D, Hallmann R, Hammerling GJ, Arnold B. Control of neonatal tolerance to tissue antigens by peripheral T cell trafficking. Science 1998;282(5392):1338–41. 18. Kurts C, Miller JF, Subramaniam RM, Carbone FR, Heath WR. Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction.

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