By E. Edward Bittar (Eds.)
With the present emphasis in melanoma examine on oncogenes and suppressor genes, and on autocrine components and their receptors, you can finish that the ''whole story''can be learn within the melanoma mobile per se. nobody could deny that the super contemporary advances in describing the molecular and mobile adjustments in melanoma cells have tremendously further to our knowing of neoplasia. yet, studying how you can translate the that means of those changes into methods of treating and, greater but, combating melanoma would require not less than as deep an knowing of the context within which it develops. the themes of this quantity have been chosen to steer the reader during the complicated sequence of occasions through which melanoma cells and their ''environment''interact to supply malignant disorder. Underlying subject matters are the range within the pathways that could result in malignancy and the fundamental heterogeneity of neoplastic mobile populations. As has frequently been stated, in melanoma no generalizations are continually real (including this one). hence, a number of the chapters needs to be considered as examples of attainable strategies and mechanisms, no longer as universally acceptable legislation.
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